BioLife Solutions Reports Second Quarter 2025 Financial Results

PR Newswire

BOTHELL, Wash., Aug. 7, 2025

Cell Processing revenue of $23.0 million, up 28% over Q2 2024

GAAP gross margin of 62% and non-GAAP adjusted gross margin of 65%

GAAP net loss of $15.8 million, inclusive of a non-cash $15.5 million IPR&D expense, and non-GAAP adjusted EBITDA of $6.1 million or 24% of revenue

Raises full-year 2025 revenue guidance to $100.0 million - $103.0 million, and full-year 2025 Cell Processing revenue guidance to $91.0 million - $93.0 million

Conference call begins at 4:30 p.m. Eastern time today

BOTHELL, Wash., Aug. 7, 2025 /PRNewswire/ -- BioLife Solutions, Inc. (Nasdaq: BLFS) ("BioLife" or the "Company"), a leading developer and supplier of cell processing tools and services for the cell and gene therapy ("CGT") market, announces financial results for the three and six months ended June 30, 2025.

BioLife Solutions Logo (PRNewsfoto/BioLife Solutions, Inc.)

Roderick de Greef, BioLife's Chairman and CEO, commented, "We delivered another strong quarter with cell processing revenue increasing 28% year-over-year and marking our seventh consecutive quarter of sequential growth. Performance was led by our biopreservation media (BPM) franchise, where we saw continued strength across both direct and distributor channels. Notably, customers with approved commercial therapies again represented approximately 40% of total BPM revenue – underscoring the recurring nature of our product and the spec'd in consistency of our model. With our media embedded in 16 approved therapies and supporting more than 250 ongoing commercial trials, including over 30 in Phase III, we've established BioLife as the default partner for clinical programs across all phases, including later stage trials where clinical success is more likely and the path to commercial revenue is clearest.

"With this momentum and improved visibility into the second half, even against an uncertain macro backdrop, we are raising our full year guidance for cell processing revenue," he added. "Continued outperformance in cell processing and meaningful year-over-year expansion in adjusted EBITDA margin reflect the operating leverage and financial benefits of our streamlined operations and focused product portfolio – positioning BioLife to deliver sustained growth and long-term shareholder value."

Second Quarter 2025 Business Highlights

The Company accounted for the PanTHERA transaction as an asset acquisition. Because the IRI cryopreservation technology was under development at the time of the transaction, it is considered in-process research and development ("IPR&D") as of the date of acquisition. The Company valued the IRP&D asset at $15.5 million, and in accordance with US GAAP, determined that the fair value of the asset should be immediately expensed. The expense is reported in our Condensed Consolidated Statements of Operations. This one-time, non-cash charge impacted GAAP EPS by approximately $0.32 and $0.33 for the three and six months ended June 30, 2025, respectively. This charge has been excluded from our non-GAAP financial results.

Second Quarter 2025 Financial Results

BioLife Solutions is presenting various financial metrics under U.S. generally accepted accounting principles (GAAP) and as adjusted (non-GAAP). In addition, BioLife Solutions is presenting Global Cooling, Inc., SciSafe, and CBS as discontinued operations for all periods presented within the Condensed Consolidated Balance Sheets and Condensed Consolidated Statements of Operations. The Condensed Consolidated Statements of Comprehensive Loss, Condensed Consolidated Statements of Shareholders' Equity, and Condensed Consolidated Statements of Cash Flows are presented on a consolidated basis for both continuing operations and discontinued operations. All amounts, percentages, and disclosures for all periods presented reflect only the continuing operations of the Company unless otherwise noted.

REVENUE

GROSS MARGIN

OPERATING LOSS FROM CONTINUING OPERATIONS

NET LOSS FROM CONTINUING OPERATIONS

LOSS PER SHARE FROM CONTINUING OPERATIONS

ADJUSTED EBITDA

CASH, CASH EQUIVALENTS, AND MARKETABLE SECURITIES

(As a result of presenting amounts in millions, rounding differences may exist in the percentages above.)

2025 Financial Guidance

BioLife Solutions is raising its 2025 revenue guidance to $100.0 million to $103.0 million from prior guidance of $95.5 million to $99.0 million, representing growth of 22% to 25% compared with 2024. This guidance is based on the following expectations:

Management expects 2025 gross margin (GAAP) in the low 60% range and adjusted gross margin (non-GAAP) in the mid-60% range, as well as a reduction in net loss (GAAP), and continued expansion of adjusted EBITDA margin (non-GAAP) compared with 2024.

Conference Call & Webcast

Management will discuss the Company's financial results, provide a general business update and answer questions during a conference call and live webcast today at 4:30 p.m. ET (1:30 p.m. PT).

To access the webcast, log onto the Investor Relations page of the BioLife Solutions website at https://www.biolifesolutions.com/earnings. In addition, the conference call will be accessible by dialing toll-free 1-833-630-0431 or 1-412-317-1808 for international callers. A webcast replay will be available approximately two hours after the call ends and will be archived on https://www.biolifesolutions.com for 90 days.

About BioLife Solutions

BioLife is a leading developer and supplier of cell processing tools and services for the CGT market. Our expertise facilitates the commercialization of new therapies by supplying solutions that maintain the health and function of biologic materials during the collection, development, manufacturing and distribution. For more information, please visit www.biolifesolutions.com, and follow BioLife on LinkedIn and X.

Cautions Regarding Forward Looking Statements

Certain statements contained in this press release are not historical facts and may be forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as "plans," "intend," "expects," "continue," "believes," "anticipates," "designed," and similar words are intended to identify forward-looking statements. Forward-looking statements are based on our current expectations and beliefs, and involve a number of risks and uncertainties that are difficult to predict and that could cause actual results to differ materially from those stated or implied by the forward-looking statements. A description of certain of these risks, uncertainties and other matters can be found in filings we make with the U.S. Securities and Exchange Commission, all of which are available at www.sec.gov. Because forward-looking statements involve risks and uncertainties, actual results and events may differ materially from results and events currently expected by us. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. We undertake no obligation to publicly update these forward-looking statements to reflect events or circumstances that occur after the date hereof or to reflect any change in its expectations with regard to these forward-looking statements or the occurrence of unanticipated events.

Non-GAAP Measures of Financial Performance

To supplement our financial statements, which are presented on the basis of U.S. generally accepted accounting principles (GAAP), the following non-GAAP measures of financial performance are included on a consolidated basis in this release: adjusted gross margin, adjusted operating expenses, adjusted operating income/(loss), adjusted net income/(loss), earnings before interest, taxes, depreciation and amortization (EBITDA), and adjusted EBITDA. A reconciliation of GAAP to adjusted non-GAAP financial measures is included as an attachment to this press release.

We believe these non-GAAP financial measures are useful to investors in assessing our operating performance. We use these financial measures internally to evaluate our operating performance and for planning and forecasting of future periods. We also believe it is in the best interests of investors to provide this non-GAAP information.

While we believe these non-GAAP financial measures provide useful supplemental information to investors, there are limitations associated with the use of these non-GAAP financial measures. These non-GAAP financial measures may not be reported by competitors, and they may not be directly comparable to similarly titled measures of other companies due to differences in calculation methodologies. The non-GAAP financial measures are not an alternative to GAAP information and are not meant to be considered in isolation or as a substitute for comparable GAAP financial measures. They should be used only as a supplement to GAAP information and should be considered only in conjunction with our consolidated financial statements prepared in accordance with GAAP.

Media & Investor Relations

At the Company

Troy Wichterman
Chief Financial Officer
(425) 402-1400
twichterman@biolifesolutions.com 

Investors

Alliance Advisors IR
Jody Cain
(310) 691-7100
jcain@allianceadvisors.com

BIOLIFE SOLUTIONS, INC.

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

(Unaudited, amounts in thousands, except share and per share amounts)


Three Months Ended
June 30,


Six Months Ended
June 30,

(In thousands, except per share and share data)

2025


2024


2025


2024








Product revenue

$               23,709


$               18,112


$               46,008


$               34,855

Service revenue

36


74


96


99

Rental revenue

1,676


1,529


3,258


3,194

Total product, rental, and service revenue

25,421


19,715


49,362


38,148

Costs and operating expenses:








Cost of product, rental, and service revenue (exclusive of Intangible asset amortization)

8,988


6,508


17,142


12,700

General and administrative

11,396


9,318


22,898


19,715

Sales and marketing

2,732


2,483


5,328


4,859

Research and development

2,719


2,029


4,923


4,104

IPR&D expense

15,521



15,521


Intangible asset amortization

708


683


1,410


1,371

Total operating expenses

42,064


21,021


67,222


42,749

Operating loss

(16,643)


(1,306)


(17,860)


(4,601)








Other income (expense):








Change in fair value of equity investments


(4,074)



(4,074)

Interest income (expense), net

684


(325)


1,365


(465)

Other income

247


146


349


399

Total other income (expense), net

931


(4,253)


1,714


(4,140)








Loss before income tax expense

(15,712)


(5,559)


(16,146)


(8,741)

Income tax expense

(126)


(1)


(140)


(18)

Net loss from continuing operations

$             (15,838)


$               (5,560)


$             (16,286)


$               (8,759)








Discontinued operations:








Loss from discontinued operations before income tax expense


(15,159)



(22,067)

Income tax expense




(114)

Loss from discontinued operations

$                      —


$             (15,159)


$                      —


$             (22,181)








Net loss

$             (15,838)


$             (20,719)


$             (16,286)


$             (30,940)








Loss from continuing operations, attributable to common shareholders:








Basic and Diluted

$             (15,838)


$               (5,560)


$             (16,286)


$               (8,759)

Loss from discontinued operations, attributable to common shareholders:








Basic and Diluted

$                      —


$             (15,159)


$                      —


$             (22,181)

Loss per share from continuing operations, attributable to common shareholders:








Basic and Diluted

$                 (0.33)


$                 (0.12)


$                 (0.34)


$                 (0.19)

Loss per share from discontinued operations, attributable to common shareholders:








Basic and Diluted

$                      —


$                 (0.33)


$                      —


$                 (0.49)

Net loss attributable to common shareholders:








Basic and Diluted

$             (15,838)


$             (20,719)


$             (16,286)


$             (30,940)

Net loss per share attributable to common shareholders:








Basic and Diluted

$                 (0.33)


$                 (0.45)


$                 (0.34)


$                 (0.68)

Weighted average shares used to compute loss per share attributable to common
shareholders:








Basic and Diluted

47,798,146


46,004,037


47,468,266


45,718,232

 

BIOLIFE SOLUTIONS, INC.

CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS

(Unaudited, amounts in thousands)


Three Months Ended

June 30,


Six Months Ended

June 30,

(In thousands)

2025


2024


2025


2024

Net loss

$    (15,838)


$    (20,719)


$    (16,286)


$    (30,940)

Other comprehensive income (loss)

38


11


47


(210)

Comprehensive loss

$    (15,800)


$    (20,708)


$    (16,239)


$    (31,150)

 

BIOLIFE SOLUTIONS, INC.

CONDENSED CONSOLIDATED BALANCE SHEET INFORMATION

(Unaudited, amounts in thousands)


June 30,


December 31,

(In thousands)

2025


2024

Cash, cash equivalents, and marketable securities

$        100,237


$        109,212

Working capital

97,120


116,027

Current assets

125,432


148,761

Current liabilities

28,312


32,734

Total assets

387,240


399,487

Long-term obligations

11,773


17,844

Accumulated deficit

(351,387)


(335,101)

Total shareholders' equity

$        347,155


$        348,909

 

BIOLIFE SOLUTIONS, INC.

CONDENSED CONSOLIDATED STATEMENT OF CASH FLOWS INFORMATION

(Unaudited, amounts in thousands)


Six Months Ended
June 30,

(In thousands)

2025


2024

Net cash provided by operating activities

$           9,095


$           1,984

Net cash used in investing activities

(66,709)


(13,656)

Net cash used in financing activities

(5,870)


(1,656)

Effects of currency translation


(65)

Net decrease in cash and cash equivalents

$       (63,484)


$       (13,393)




Cash and cash equivalents – beginning of period

$         95,386


$         35,438

Cash and cash equivalents – end of period

31,902


22,045




Marketable securities

68,335


14,808




Total cash, cash equivalents, and marketable securities

$       100,237


$         36,853

 

BIOLIFE SOLUTIONS, INC.

RECONCILIATION OF GAAP GROSS PROFIT TO NON-GAAP ADJUSTED GROSS MARGIN

(Unaudited, amounts in thousands)


Three Months Ended
June 30,


Six Months Ended
June 30,

(In thousands)

2025


2024


2025


2024

Total revenues

$     25,421


$     19,715


$     49,362


$     38,148

Cost of revenues

(8,988)


(6,508)


(17,142)


(12,700)

COGS intangible asset amortization

(602)


(577)


(1,198)


(1,159)

GROSS PROFIT

$     15,831


$     12,630


$     31,022


$     24,289

GROSS MARGIN

62 %


64 %


63 %


64 %








ADJUSTMENTS TO GROSS PROFIT:








Gain on disposal of assets



(12)


Intangible asset amortization

602


577


1,198


1,159

ADJUSTED GROSS PROFIT

$     16,433


$     13,207


$     32,208


$     25,448

ADJUSTED GROSS MARGIN

65 %


67 %


65 %


67 %

 

BIOLIFE SOLUTIONS, INC.

RECONCILIATION OF GAAP OPERATING EXPENSES FROM CONTINUING OPERATIONS TO NON-
GAAP ADJUSTED OPERATING EXPENSES FROM CONTINUING OPERATIONS

(Unaudited, amounts in thousands)


Three Months Ended
June 30,


Six Months Ended
June 30,

(In thousands)

2025


2024


2025


2024

OPERATING EXPENSES FROM
CONTINUING OPERATIONS

$        42,064


$        21,021


$        67,222


$        42,749








ADJUSTMENTS TO OPERATING
EXPENSES FROM CONTINUING
OPERATIONS:








Cost of product, rental, and service
revenues

(8,988)


(6,508)


(17,142)


(12,700)

Acquisition and divestiture costs(1)

59


(134)


(941)


(371)

Severance costs



(416)


IPR&D expense

(15,521)



(15,521)


Intangible asset amortization

(708)


(683)


(1,410)


(1,371)

Loss on disposal of assets



10


Other income


300



300

ADJUSTED OPERATING EXPENSES
FROM CONTINUING OPERATIONS

$        16,906


$        13,996


$        31,802


$        28,607


(1) During the six months ended June 2025, we incurred $0.5 million in transaction expenses resulting from the PanTHERA acquisition, which is recorded in IPR&D expense on our Condensed Consolidated Statement of Operations. We reclassified $0.1 million incurred and recorded in Q1-2025 to conform with this current presentation.

 

BIOLIFE SOLUTIONS, INC.

RECONCILIATION OF GAAP OPERATING LOSS FROM CONTINUING OPERATIONS TO NON-GAAP
ADJUSTED OPERATING (LOSS) / INCOME FROM CONTINUING OPERATIONS

(Unaudited, amounts in thousands)


Three Months Ended
June 30,


Six Months Ended
June 30,

(In thousands)

2025


2024


2025


2024

OPERATING LOSS FROM CONTINUING
OPERATIONS

$       (16,643)


$        (1,306)


$       (17,860)


$        (4,601)








ADJUSTMENTS TO OPERATING LOSS
FROM CONTINUING OPERATIONS















Acquisition and divestiture costs(1)

(59)


134


941


371

Severance costs



416


IPR&D expense

15,521



15,521


Intangible asset amortization

708


683


1,410


1,371

Gain on disposal of assets



(10)


Other income


(300)



(300)

ADJUSTED OPERATING (LOSS) /
INCOME FROM CONTINUING
OPERATIONS

$           (473)


$           (789)


$             418


$        (3,159)


(1) During the six months ended June 2025, we incurred $0.5 million in transaction expenses resulting from the PanTHERA acquisition, which is recorded in IPR&D expense on our Condensed Consolidated Statement of Operations. We reclassified $0.1 million incurred and recorded in Q1-2025 to conform with this current presentation.

 

BIOLIFE SOLUTIONS, INC.

RECONCILIATION OF GAAP NET LOSS FROM CONTINUING OPERATIONS TO NON-GAAP
ADJUSTED NET INCOME / (LOSS) FROM CONTINUING OPERATIONS

(Unaudited, amounts in thousands)


Three Months Ended
June 30,


Six Months Ended
June 30,

(In thousands)

2025


2024


2025


2024

NET LOSS FROM CONTINUING
OPERATIONS

$       (15,838)


$        (5,560)


$       (16,286)


$        (8,759)








ADJUSTMENTS TO NET LOSS FROM
CONTINUING OPERATIONS















Acquisition and divestiture costs(1)

(59)


134


941


371

Severance costs



416


IPR&D expense

15,521



15,521


Intangible asset amortization

708


683


1,410


1,371

Gain on disposal of assets



(10)


Change in fair value of equity investments


4,074



4,074

Income tax expense

126


1


140


18

Other income


(300)



(300)

ADJUSTED NET INCOME / (LOSS)
FROM CONTINUING OPERATIONS

$             458


$           (968)


$          2,132


$        (3,225)


(1) During the six months ended June 2025, we incurred $0.5 million in transaction expenses resulting from the PanTHERA acquisition, which is recorded in IPR&D expense on our Condensed Consolidated Statement of Operations. We reclassified $0.1 million incurred and recorded in Q1-2025 to conform with this current presentation.

 

BIOLIFE SOLUTIONS, INC.

RECONCILIATION OF GAAP NET LOSS FROM CONTINUING OPERATIONS TO NON-GAAP
ADJUSTED EBITDA FROM CONTINUING OPERATIONS

(Unaudited, amounts in thousands)


Three Months Ended
June 30,


Six Months Ended
June 30,

(In thousands)

2025


2024


2025


2024

NET LOSS FROM CONTINUING
OPERATIONS

$    (15,838)


$     (5,560)


$    (16,286)


$     (8,759)








ADJUSTMENTS:








Interest (income) expense, net

(684)


325


(1,365)


465

Accretion of available-for-sale investments

(200)


(137)


(305)


(320)

Income tax expense

126


1


140


18

Depreciation

673


746


1,356


1,513

Intangible asset amortization

708


683


1,410


1,371

EBITDA

$    (15,215)


$     (3,942)


$    (15,050)


$     (5,712)








OTHER ADJUSTMENTS:








Share-based compensation (non-cash)

5,849


3,971


10,002


8,099

Acquisition and divestiture costs(1)

(59)


134


941


371

Severance costs



416


IPR&D expense

15,521



15,521


Gain on disposal of assets



(10)


Change in fair value of equity investments


4,074



4,074

Other income


(300)



(300)

ADJUSTED EBITDA FROM CONTINUING
OPERATIONS

$       6,096


$       3,937


$     11,820


$       6,532

% of Revenue

24 %


20 %


24 %


17 %


(1) During the six months ended June 2025, we incurred $0.5 million in transaction expenses resulting from the PanTHERA acquisition, which is recorded in IPR&D expense on our Condensed Consolidated Statement of Operations. We reclassified $0.1 million incurred and recorded in Q1-2025 to conform with this current presentation.

 

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SOURCE BioLife Solutions, Inc.